Interaction between PAK and Nck: a Template for Nck Targets and Role of PAK Autophosphorylation

The kinase PAK binds tightly to the SH3 domain of its partner PIX via a central proline-rich sequence. A different N-terminal sequence allows αPAK to bind an SH3 domain of the adaptor Nck. The Nck SH3[2] domain interacts equally with an 18-mer PAK-derived peptide and full-length αPAK. Detailed analy...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Zhao, Zhou-shen, Manser, Edward, Lim, Louis
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85736/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10805734/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.11.3906-3917.2000
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