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Differential T-Cell Antigen Receptor Signaling Mediated by the Src Family Kinases Lck and Fyn

Src family tyrosine kinases play a key role in T-cell antigen receptor (TCR) signaling. They are responsible for the initial tyrosine phosphorylation of the receptor, leading to the recruitment of the ZAP-70 tyrosine kinase, as well as the subsequent phosphorylation and activation of ZAP-70. Molecul...

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Detalhes bibliográficos
Main Authors: Denny, Michael F., Patai, Barbara, Straus, David B.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC85301/
https://ncbi.nlm.nih.gov/pubmed/10648627
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