Differential T-Cell Antigen Receptor Signaling Mediated by the Src Family Kinases Lck and Fyn

Src family tyrosine kinases play a key role in T-cell antigen receptor (TCR) signaling. They are responsible for the initial tyrosine phosphorylation of the receptor, leading to the recruitment of the ZAP-70 tyrosine kinase, as well as the subsequent phosphorylation and activation of ZAP-70. Molecul...

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Bibliographic Details
Main Authors: Denny, Michael F., Patai, Barbara, Straus, David B.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC85301/
https://ncbi.nlm.nih.gov/pubmed/10648627
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