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Active Repression of Methylated Genes by the Chromosomal Protein MBD1

MBD1 belongs to a family of mammalian proteins that share a methyl-CpG binding domain. Previous work has shown that MBD1 binds to methylated sites in vivo and in vitro and can repress transcription from methylated templates in transcription extracts and in cultured cells. In the present study we est...

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Dettagli Bibliografici
Pubblicato in:Mol Cell Biol
Autori principali: Ng, Huck-Hui, Jeppesen, Peter, Bird, Adrian
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2000
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85293/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10648624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.4.1394-1406.2000
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