Active Repression of Methylated Genes by the Chromosomal Protein MBD1

MBD1 belongs to a family of mammalian proteins that share a methyl-CpG binding domain. Previous work has shown that MBD1 binds to methylated sites in vivo and in vitro and can repress transcription from methylated templates in transcription extracts and in cultured cells. In the present study we est...

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Εκδόθηκε σε:	Mol Cell Biol
Κύριοι συγγραφείς:	Ng, Huck-Hui, Jeppesen, Peter, Bird, Adrian
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Taylor & Francis 2000
Θέματα:	Transcriptional Regulation
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85293/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10648624/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.4.1394-1406.2000
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