Active Repression of Methylated Genes by the Chromosomal Protein MBD1
MBD1 belongs to a family of mammalian proteins that share a methyl-CpG binding domain. Previous work has shown that MBD1 binds to methylated sites in vivo and in vitro and can repress transcription from methylated templates in transcription extracts and in cultured cells. In the present study we est...
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| Veröffentlicht in: | Mol Cell Biol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2000
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85293/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10648624/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.4.1394-1406.2000 |
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