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Active Repression of Methylated Genes by the Chromosomal Protein MBD1

MBD1 belongs to a family of mammalian proteins that share a methyl-CpG binding domain. Previous work has shown that MBD1 binds to methylated sites in vivo and in vitro and can repress transcription from methylated templates in transcription extracts and in cultured cells. In the present study we est...

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Publicat a:Mol Cell Biol
Autors principals: Ng, Huck-Hui, Jeppesen, Peter, Bird, Adrian
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2000
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85293/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10648624/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.4.1394-1406.2000
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