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Sequential Regulation of the Small GTPase Rap1 in Human Platelets
Rap1, a small GTPase of the Ras family, is ubiquitously expressed and particularly abundant in platelets. Previously we have shown that Rap1 is rapidly activated after stimulation of human platelets with α-thrombin. For this activation, a phospholipase C-mediated increase in intracellular calcium is...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Microbiology
2000
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC85194/ https://ncbi.nlm.nih.gov/pubmed/10629034 |
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