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Rapid Ca2+-mediated activation of Rap1 in human platelets.

Rap1 is a small, Ras-like GTPase whose function and regulation are still largely unknown. We have developed a novel assay to monitor the active, GTP-bound form of Rap1 based on the differential affinity of Rap1GTP and Rap1GDP for the Rap binding domain of RalGDS (RBD). Stimulation of blood platelets...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Franke, B, Akkerman, J W, Bos, J L
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1997
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC1169632/
https://ncbi.nlm.nih.gov/pubmed/9029146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.2.252
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