The Phosphoinositide 3-OH Kinase/AKT2 Pathway as a Critical Target for Farnesyltransferase Inhibitor-Induced Apoptosis
Farnesyltransferase inhibitors (FTIs) represent a novel class of anticancer drugs that exhibit a remarkable ability to inhibit malignant transformation without toxicity to normal cells. However, the mechanism by which FTIs inhibit tumor growth is not well understood. Here, we demonstrate that FTI-27...
محفوظ في:
| الحاوية / القاعدة: | Mol Cell Biol |
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| المؤلفون الرئيسيون: | , , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Taylor & Francis
2000
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC85069/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10594016/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.1.139-148.2000 |
| الوسوم: |
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