Accelerated Mammary Tumor Development in Mutant Polyomavirus Middle T Transgenic Mice Expressing Elevated Levels of Either the Shc or Grb2 Adapter Protein

The Grb2 and Shc adapter proteins play critical roles in coupling activated growth factor receptors to several cellular signaling pathways. To assess the role of these molecules in mammary epithelial development and tumorigenesis, we have generated transgenic mice which individually express the Grb2...

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Xehetasun bibliografikoak

Argitaratua izan da:	Mol Cell Biol
Egile Nagusiak:	Rauh, Michael J., Blackmore, Valerie, Andrechek, Eran R., Tortorice, Christopher G., Daly, Roger, Lai, Venus Ka-Man, Pawson, Tony, Cardiff, Robert D., Siegel, Peter M., Muller, William J.
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Taylor & Francis 1999
Gaiak:	Cell Growth and Development
Sarrera elektronikoa:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84901/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10567542/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.12.8169
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