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Mechanistic Basis for Coding End Sequence Effects in the Initiation of V(D)J Recombination

V(D)J recombination is directed by recombination signal sequences. However, the flanking coding end sequence can markedly affect the frequency of the initiation of V(D)J recombination in vivo. Here we demonstrate that the coding end sequence effect can be qualitatively and quantitatively recapitulat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yu, Kefei, Lieber, Michael R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84894/
https://ncbi.nlm.nih.gov/pubmed/10567535
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