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Failure of Hairpin-Ended and Nicked DNA To Activate DNA-Dependent Protein Kinase: Implications for V(D)J Recombination

V(D)J recombination is initiated by a coordinated cleavage reaction that nicks DNA at two sites and then forms a hairpin coding end and blunt signal end at each site. Following cleavage, the DNA ends are joined by a process that is incompletely understood but nevertheless depends on DNA-dependent pr...

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Publicat a:Mol Cell Biol
Autors principals: Smider, Vaughn, Rathmell, W. Kimryn, Brown, Greg, Lewis, Susanna, Chu, Gilbert
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109268/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9774698/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.18.11.6853
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