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RanGTP-Regulated Interactions of CRM1 with Nucleoporins and a Shuttling DEAD-Box Helicase

CRM1 is an export receptor mediating rapid nuclear exit of proteins and RNAs to the cytoplasm. CRM1 export cargoes include proteins with a leucine-rich nuclear export signal (NES) that bind directly to CRM1 in a trimeric complex with RanGTP. Using a quantitative CRM1-NES cargo binding assay, signifi...

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Detalhes bibliográficos
Main Authors: Askjaer, Peter, Bachi, Angela, Wilm, Matthias, Bischoff, F. Ralf, Weeks, Daniel L., Ogniewski, Vera, Ohno, Mutsuhito, Niehrs, Christof, Kjems, Jørgen, Mattaj, Iain W., Fornerod, Maarten
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84588/
https://ncbi.nlm.nih.gov/pubmed/10454574
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