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RanGTP-Regulated Interactions of CRM1 with Nucleoporins and a Shuttling DEAD-Box Helicase

CRM1 is an export receptor mediating rapid nuclear exit of proteins and RNAs to the cytoplasm. CRM1 export cargoes include proteins with a leucine-rich nuclear export signal (NES) that bind directly to CRM1 in a trimeric complex with RanGTP. Using a quantitative CRM1-NES cargo binding assay, signifi...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Askjaer, Peter, Bachi, Angela, Wilm, Matthias, Bischoff, F. Ralf, Weeks, Daniel L., Ogniewski, Vera, Ohno, Mutsuhito, Niehrs, Christof, Kjems, Jørgen, Mattaj, Iain W., Fornerod, Maarten
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84588/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454574/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.6276
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