Identification by In Vivo Genomic Footprinting of a Transcriptional Switch Containing NF-κB and Sp1 That Regulates the IκBα Promoter

In unstimulated cells, NF-κB transcription factors are retained in the cytoplasm by inhibitory IκB proteins. Upon stimulation by multiple inducers including cytokines or viruses, IκBα is rapidly phosphorylated and degraded, resulting in the release of NF-κB and the subsequent increase in NF-κB-regul...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Algarté, Michèle, Kwon, Hakju, Génin, Pierre, Hiscott, John
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 1999
Assuntos:	Transcriptional Regulation
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84541/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.6140
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