Identification by In Vivo Genomic Footprinting of a Transcriptional Switch Containing NF-κB and Sp1 That Regulates the IκBα Promoter

In unstimulated cells, NF-κB transcription factors are retained in the cytoplasm by inhibitory IκB proteins. Upon stimulation by multiple inducers including cytokines or viruses, IκBα is rapidly phosphorylated and degraded, resulting in the release of NF-κB and the subsequent increase in NF-κB-regul...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Algarté, Michèle, Kwon, Hakju, Génin, Pierre, Hiscott, John
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84541/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10454561/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.9.6140
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