Alpha/Beta Interferon Promotes Transcription and Inhibits Replication of Borna Disease Virus in Persistently Infected Cells

Borna disease virus (BDV) is a noncytolytic RNA virus that can replicate in the central nervous system (CNS) of mice. This study shows that BDV multiplication was efficiently blocked in transgenic mice that express mouse alpha-1 interferon (IFN-α1) in astrocytes. To investigate whether endogenous vi...

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Hlavní autoři: Staeheli, Peter, Sentandreu, Maria, Pagenstecher, Axel, Hausmann, Jürgen
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
Virus-Cell Interactions
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC115066/
https://ncbi.nlm.nih.gov/pubmed/11483767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.17.8216-8223.2001
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