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Alpha/Beta Interferon and Gamma Interferon Synergize To Inhibit the Replication of Herpes Simplex Virus Type 1

In vivo evidence suggests that T-cell-derived gamma interferon (IFN-γ) can directly inhibit the replication of herpes simplex virus type 1 (HSV-1). However, IFN-γ is a weak inhibitor of HSV-1 replication in vitro. We have found that IFN-γ synergizes with the innate IFNs (IFN-α and -β) to potently in...

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Bibliografiska uppgifter
Huvudupphovsmän: Sainz, Bruno, Halford, William P.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2002
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC136787/
https://ncbi.nlm.nih.gov/pubmed/12388715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.22.11541-11550.2002
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