A Novel Role in DNA Metabolism for the Binding of Fen1/Rad27 to PCNA and Implications for Genetic Risk

Fen1/Rad27 nuclease activity, which is important in DNA metabolism, is stimulated by proliferating cell nuclear antigen (PCNA) in vitro. The in vivo role of the PCNA interaction was investigated in the yeast Rad27. A nuclease-defective rad27 mutation had a dominant-negative effect that was suppresse...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Gary, Ronald, Park, Min S., Nolan, John P., Cornelius, Helen L., Kozyreva, Olga G., Tran, Hiep T., Lobachev, Kirill S., Resnick, Michael A., Gordenin, Dmitry A.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 1999
Pynciau:
DNA Dynamics and Chromosome Structure
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC84380/
https://ncbi.nlm.nih.gov/pubmed/10409728
Tagiau: Ychwanegu Tag
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