A Novel Role in DNA Metabolism for the Binding of Fen1/Rad27 to PCNA and Implications for Genetic Risk

Fen1/Rad27 nuclease activity, which is important in DNA metabolism, is stimulated by proliferating cell nuclear antigen (PCNA) in vitro. The in vivo role of the PCNA interaction was investigated in the yeast Rad27. A nuclease-defective rad27 mutation had a dominant-negative effect that was suppresse...

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Bibliografische gegevens
Hoofdauteurs: Gary, Ronald, Park, Min S., Nolan, John P., Cornelius, Helen L., Kozyreva, Olga G., Tran, Hiep T., Lobachev, Kirill S., Resnick, Michael A., Gordenin, Dmitry A.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 1999
Onderwerpen:
DNA Dynamics and Chromosome Structure
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC84380/
https://ncbi.nlm.nih.gov/pubmed/10409728
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