Atm Inactivation Results in Aberrant Telomere Clustering during Meiotic Prophase

A-T (ataxia telangiectasia) individuals frequently display gonadal atrophy, and Atm(−/−) mice show spermatogenic failure due to arrest at prophase of meiosis I. Chromosomal movements take place during meiotic prophase, with telomeres congregating on the nuclear envelope to transiently form a cluster...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Pandita, Tej K., Westphal, Christoph H., Anger, Melanie, Sawant, Satin G., Geard, Charles R., Pandita, Raj K., Scherthan, Harry
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	DNA Dynamics and Chromosome Structure
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84352/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10373558/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.7.5096
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