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Atm Inactivation Results in Aberrant Telomere Clustering during Meiotic Prophase

A-T (ataxia telangiectasia) individuals frequently display gonadal atrophy, and Atm(−/−) mice show spermatogenic failure due to arrest at prophase of meiosis I. Chromosomal movements take place during meiotic prophase, with telomeres congregating on the nuclear envelope to transiently form a cluster...

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Hlavní autoři: Pandita, Tej K., Westphal, Christoph H., Anger, Melanie, Sawant, Satin G., Geard, Charles R., Pandita, Raj K., Scherthan, Harry
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 1999
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC84352/
https://ncbi.nlm.nih.gov/pubmed/10373558
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