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Meiotic Telomere Distribution and Sertoli Cell Nuclear Architecture Are Altered in Atm- and Atm-p53-Deficient Mice

The ataxia telangiectasia mutant (ATM) protein is an intrinsic part of the cell cycle machinery that surveys genomic integrity and responses to genotoxic insult. Individuals with ataxia telangiectasia as well as Atm(−/−) mice are predisposed to cancer and are infertile due to spermatogenesis disrupt...

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Detalhes bibliográficos
Main Authors: Scherthan, Harry, Jerratsch, Martin, Dhar, Sonu, Wang, Y. Alan, Goff, Stephen P., Pandita, Tej K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86364/
https://ncbi.nlm.nih.gov/pubmed/11003672
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