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Meiotic Telomere Distribution and Sertoli Cell Nuclear Architecture Are Altered in Atm- and Atm-p53-Deficient Mice

The ataxia telangiectasia mutant (ATM) protein is an intrinsic part of the cell cycle machinery that surveys genomic integrity and responses to genotoxic insult. Individuals with ataxia telangiectasia as well as Atm(−/−) mice are predisposed to cancer and are infertile due to spermatogenesis disrupt...

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Vydáno v:Mol Cell Biol
Hlavní autoři: Scherthan, Harry, Jerratsch, Martin, Dhar, Sonu, Wang, Y. Alan, Goff, Stephen P., Pandita, Tej K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Taylor & Francis 2000
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On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86364/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11003672/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.20.7773-7783.2000
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