Molecular Determinants of the Estrogen Receptor-Coactivator Interface

Transcriptional activation by the estrogen receptor is mediated through its interaction with coactivator proteins upon ligand binding. By systematic mutagenesis, we have identified a group of conserved hydrophobic residues in the ligand binding domain that are required for binding the p160 family of...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Mak, Ho Yi, Hoare, Sue, Henttu, Pirkko M. A., Parker, Malcolm G.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207113/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3895
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