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Molecular Determinants of the Estrogen Receptor-Coactivator Interface

Transcriptional activation by the estrogen receptor is mediated through its interaction with coactivator proteins upon ligand binding. By systematic mutagenesis, we have identified a group of conserved hydrophobic residues in the ligand binding domain that are required for binding the p160 family of...

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Main Authors: Mak, Ho Yi, Hoare, Sue, Henttu, Pirkko M. A., Parker, Malcolm G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC84247/
https://ncbi.nlm.nih.gov/pubmed/10207113
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