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Molecular Determinants of the Estrogen Receptor-Coactivator Interface

Transcriptional activation by the estrogen receptor is mediated through its interaction with coactivator proteins upon ligand binding. By systematic mutagenesis, we have identified a group of conserved hydrophobic residues in the ligand binding domain that are required for binding the p160 family of...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Mak, Ho Yi, Hoare, Sue, Henttu, Pirkko M. A., Parker, Malcolm G.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84247/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207113/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3895
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