Molecular Determinants of the Estrogen Receptor-Coactivator Interface

Transcriptional activation by the estrogen receptor is mediated through its interaction with coactivator proteins upon ligand binding. By systematic mutagenesis, we have identified a group of conserved hydrophobic residues in the ligand binding domain that are required for binding the p160 family of...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Mak, Ho Yi, Hoare, Sue, Henttu, Pirkko M. A., Parker, Malcolm G.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 1999
Soggetti:	Transcriptional Regulation
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84247/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207113/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3895
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