Insulin-Like Growth Factor I Synergizes with Interleukin 4 for Hematopoietic Cell Proliferation Independent of Insulin Receptor Substrate Expression

In the present study, we investigated the potential role of insulin-like growth factor I (IGF-I) receptor (IGF-IR) in cell proliferation by overexpressing it in 32D myeloid progenitor cells. The overexpression of IGF-IR caused the transfectants to proliferate in response to IGF-I in the absence of i...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Soon, Lilian, Flechner, Lawrence, Gutkind, J. Silvio, Wang, Lu-Hai, Baserga, Renato, Pierce, Jacalyn H., Li, Weiqun
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84225/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207105/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3816
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