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Insulin-Like Growth Factor I Synergizes with Interleukin 4 for Hematopoietic Cell Proliferation Independent of Insulin Receptor Substrate Expression

In the present study, we investigated the potential role of insulin-like growth factor I (IGF-I) receptor (IGF-IR) in cell proliferation by overexpressing it in 32D myeloid progenitor cells. The overexpression of IGF-IR caused the transfectants to proliferate in response to IGF-I in the absence of i...

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Soon, Lilian, Flechner, Lawrence, Gutkind, J. Silvio, Wang, Lu-Hai, Baserga, Renato, Pierce, Jacalyn H., Li, Weiqun
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 1999
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84225/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207105/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3816
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