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Insulin-Like Growth Factor I Synergizes with Interleukin 4 for Hematopoietic Cell Proliferation Independent of Insulin Receptor Substrate Expression

In the present study, we investigated the potential role of insulin-like growth factor I (IGF-I) receptor (IGF-IR) in cell proliferation by overexpressing it in 32D myeloid progenitor cells. The overexpression of IGF-IR caused the transfectants to proliferate in response to IGF-I in the absence of i...

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Detalhes bibliográficos
Main Authors: Soon, Lilian, Flechner, Lawrence, Gutkind, J. Silvio, Wang, Lu-Hai, Baserga, Renato, Pierce, Jacalyn H., Li, Weiqun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84225/
https://ncbi.nlm.nih.gov/pubmed/10207105
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