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Herpesviruses in the Activated Phosphatidylinositol-3-Kinase-δ Syndrome

The phosphatidylinositol-3-kinase (PI3K)/Akt pathway is important for multiple stages of herpesvirus replication including virus entry, replication, latency, and reactivation. Recently, patients with gain-of-function mutations in the p110δ-catalytic subunit of PI3K or in the p85-regulatory subunit o...

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Bibliografiske detaljer
Hovedforfatter: Jeffrey I. Cohen
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2018-02-01
Serier:Frontiers in Immunology
Fag:
Online adgang:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00237/full
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