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The Chicken β-Globin 5′HS4 Boundary Element Blocks Enhancer-Mediated Suppression of Silencing

A constitutive DNase I-hypersensitive site 5′ of the chicken β-globin locus, termed 5′HS4 or cHS4, has been shown to insulate a promoter from the effect of an upstream enhancer and to reduce position effects on mini-white expression in Drosophila cells; on the basis of these findings, it has been de...

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Main Authors: Walters, Mark C., Fiering, Steven, Bouhassira, Eric E., Scalzo, David, Goeke, Scott, Magis, Wendy, Garrick, David, Whitelaw, Emma, Martin, David I. K.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC84188/
https://ncbi.nlm.nih.gov/pubmed/10207095
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