Cumulative Effect of Phosphorylation of pRB on Regulation of E2F Activity

The product of the retinoblastoma susceptibility gene, pRB, is a nuclear phosphoprotein that controls cell growth by binding to and suppressing the activities of transcription factors such as the E2F family. Transactivation activity is inhibited when E2F is bound to hypophosphorylated pRB and releas...

Full description

Bibliographic Details

Published in:	Mol Cell Biol
Main Authors:	Brown, Vivette D., Phillips, Robert A., Gallie, Brenda L.
Format:	Artigo
Language:	Inglês
Published:	Taylor & Francis 1999
Subjects:	Transcriptional Regulation
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84119/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207050/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3246
Tags:	Add Tag No Tags, Be the first to tag this record!