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Cumulative Effect of Phosphorylation of pRB on Regulation of E2F Activity

The product of the retinoblastoma susceptibility gene, pRB, is a nuclear phosphoprotein that controls cell growth by binding to and suppressing the activities of transcription factors such as the E2F family. Transactivation activity is inhibited when E2F is bound to hypophosphorylated pRB and releas...

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Bibliografske podrobnosti
izdano v:Mol Cell Biol
Principais autores: Brown, Vivette D., Phillips, Robert A., Gallie, Brenda L.
Format: Artigo
Jezik:Inglês
Izdano: Taylor & Francis 1999
Teme:
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84119/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10207050/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.5.3246
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