Regulation of V(D)J Recombination by Transcriptional Promoters

Enhancer elements potentiate the rearrangement of antigen receptor loci via changes in the accessibility of gene segment clusters to V(D)J recombinase. Here, we show that enhancer activity per se is insufficient to target T-cell receptor β miniloci for DβJβ recombination. Instead, a promoter situate...

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Dades bibliogràfiques

Publicat a:	Mol Cell Biol
Autors principals:	Sikes, Michael L., Suarez, Cristina C., Oltz, Eugene M.
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis 1999
Matèries:	DNA Dynamics and Chromosome Structure
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84070/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082543/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2773
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