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The T cell receptor β enhancer promotes access and pairing of Dβ and Jβ gene segments during V(D)J recombination
The precise function of cis elements in regulating V(D)J recombination is still controversial. Here, we determined the effect of inactivation of the TCRβ enhancer (Eβ) on cleavage and rearrangement of Dβ1, Dβ2, Jβ1, and Jβ2 gene segments in CD4(-)CD8(-) [double-negative (DN)] and CD4(+)CD8(+) [doubl...
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| 主要な著者: | , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
National Academy of Sciences
2003
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC263837/ https://ncbi.nlm.nih.gov/pubmed/14593206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2235807100 |
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