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The T cell receptor β enhancer promotes access and pairing of Dβ and Jβ gene segments during V(D)J recombination
The precise function of cis elements in regulating V(D)J recombination is still controversial. Here, we determined the effect of inactivation of the TCRβ enhancer (Eβ) on cleavage and rearrangement of Dβ1, Dβ2, Jβ1, and Jβ2 gene segments in CD4(-)CD8(-) [double-negative (DN)] and CD4(+)CD8(+) [doubl...
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| Autori principali: | , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2003
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC263837/ https://ncbi.nlm.nih.gov/pubmed/14593206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2235807100 |
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