Regulation of V(D)J Recombination by Transcriptional Promoters

Enhancer elements potentiate the rearrangement of antigen receptor loci via changes in the accessibility of gene segment clusters to V(D)J recombinase. Here, we show that enhancer activity per se is insufficient to target T-cell receptor β miniloci for DβJβ recombination. Instead, a promoter situate...

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Detalles Bibliográficos

Publicado en:	Mol Cell Biol
Principais autores:	Sikes, Michael L., Suarez, Cristina C., Oltz, Eugene M.
Formato:	Artigo
Idioma:	Inglês
Publicado:	Taylor & Francis 1999
Assuntos:	DNA Dynamics and Chromosome Structure
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC84070/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10082543/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.4.2773
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