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A V(D)J recombinase-inducible B-cell line: role of transcriptional enhancer elements in directing V(D)J recombination.

Rapid analysis of mechanisms that regulate V(D)J recombination has been hampered by the lack of appropriate cell systems that reproduce aspects of normal prelymphocyte physiology in which the recombinase is activated, accessible antigen receptor loci are rearranged, and rearrangement status is fixed...

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Publicat a:Mol Cell Biol
Autors principals: Oltz, E M, Alt, F W, Lin, W C, Chen, J, Taccioli, G, Desiderio, S, Rathbun, G
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 1993
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC364681/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8413222/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.13.10.6223-6230.1993
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