The Paired-Domain Transcription Factor Pax8 Binds to the Upstream Enhancer of the Rat Sodium/Iodide Symporter Gene and Participates in Both Thyroid-Specific and Cyclic-AMP-Dependent Transcription

The gene encoding the Na/I symporter (NIS) is expressed at high levels only in thyroid follicular cells, where its expression is regulated by the thyroid-stimulating hormone via the second messenger, cyclic AMP (cAMP). In this study, we demonstrate the presence of an enhancer that is located between...

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Main Authors: Ohno, Makoto, Zannini, Mariastella, Levy, Orlie, Carrasco, Nancy, di Lauro, Roberto
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 1999
Teme:
Transcriptional Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC83998/
https://ncbi.nlm.nih.gov/pubmed/10022892
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