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The Paired-Domain Transcription Factor Pax8 Binds to the Upstream Enhancer of the Rat Sodium/Iodide Symporter Gene and Participates in Both Thyroid-Specific and Cyclic-AMP-Dependent Transcription

The gene encoding the Na/I symporter (NIS) is expressed at high levels only in thyroid follicular cells, where its expression is regulated by the thyroid-stimulating hormone via the second messenger, cyclic AMP (cAMP). In this study, we demonstrate the presence of an enhancer that is located between...

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Bibliografiske detaljer
Udgivet i:Mol Cell Biol
Principais autores: Ohno, Makoto, Zannini, Mariastella, Levy, Orlie, Carrasco, Nancy, di Lauro, Roberto
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 1999
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83998/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10022892/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.3.2051
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