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Chloride channel-3 regulates sodium-iodide symporter expression and localization in the thyroids of mice on a high-iodide diet

IntroductionCertain chloride channels and H+/Cl− antiporters, such as chloride channel 3 (ClC-3), are expressed at the apical pole of thyrocytes, facilitating iodide (I−) efflux. However, the relationship between ClC-3 and I− uptake remains unclear. Additionally, whether ClC-3 and reactive oxygen sp...

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Hlavní autoři: Meisheng Yu, Zhiqin Deng, Ke Wang, Xiangzhong Zhang
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2025-03-01
Edice:Frontiers in Nutrition
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fnut.2025.1537221/full
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