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Wild-Type P53 Induces Sodium/Iodide Symporter Expression Allowing Radioiodide Therapy in Anaplastic Thyroid Cancer

Aims: Anaplastic thyroid cancer(ATC) is one of the most aggressive solid tumors. Mutations in the p53 gene are common in anaplastic thyroid cancer, but the effects of p53 mutations are yet to be elucidated. Here, we investigated the role of p53 in ATC. Methods: p53 mutation was detect by immunohisto...

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Váldodahkkit: Lin Liu, Dan Li, Zhengqi Chen, Jian Yang, Yushui Ma, Haidong Cai, Chengxiang Shan, Zhongwei Lv, Xiaoping Zhang
Materiálatiipa: Artigo
Giella:Inglês
Almmustuhtton: Cell Physiol Biochem Press GmbH & Co KG 2017-09-01
Ráidu:Cellular Physiology and Biochemistry
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Liŋkkat:https://www.karger.com/Article/FullText/481640
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