Cell Growth Inhibition by Farnesyltransferase Inhibitors Is Mediated by Gain of Geranylgeranylated RhoB

Recent results have shown that the ability of farnesyltransferase inhibitors (FTIs) to inhibit malignant cell transformation and Ras prenylation can be separated. We proposed previously that farnesylated Rho proteins are important targets for alternation by FTIs, based on studies of RhoB (the FTI-Rh...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Du, Wei, Lebowitz, Peter F., Prendergast, George C.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 1999
Fag:	Cell Growth and Development
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10022870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.3.1831
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