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RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage

The effect of neoplastic transformation on the response to genotoxic stress is of significant clinical interest. In this study, we offer genetic evidence that the apoptotic response of neoplastically transformed cells to DNA damage requires RhoB, a member of the Rho family of actin cytoskeletal regu...

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Bibliografische gegevens
Hoofdauteurs: Liu, Ai-xue, Cerniglia, George J., Bernhard, Eric J., Prendergast, George C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The National Academy of Sciences 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC33444/
https://ncbi.nlm.nih.gov/pubmed/11353846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111137198
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