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RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage

The effect of neoplastic transformation on the response to genotoxic stress is of significant clinical interest. In this study, we offer genetic evidence that the apoptotic response of neoplastically transformed cells to DNA damage requires RhoB, a member of the Rho family of actin cytoskeletal regu...

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Detalhes bibliográficos
Main Authors: Liu, Ai-xue, Cerniglia, George J., Bernhard, Eric J., Prendergast, George C.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC33444/
https://ncbi.nlm.nih.gov/pubmed/11353846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111137198
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