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RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage

The effect of neoplastic transformation on the response to genotoxic stress is of significant clinical interest. In this study, we offer genetic evidence that the apoptotic response of neoplastically transformed cells to DNA damage requires RhoB, a member of the Rho family of actin cytoskeletal regu...

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Udgivet i:Proc Natl Acad Sci U S A
Principais autores: Liu, Ai-xue, Cerniglia, George J., Bernhard, Eric J., Prendergast, George C.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2001
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC33444/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11353846/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.111137198
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