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RhoB is required to mediate apoptosis in neoplastically transformed cells after DNA damage
The effect of neoplastic transformation on the response to genotoxic stress is of significant clinical interest. In this study, we offer genetic evidence that the apoptotic response of neoplastically transformed cells to DNA damage requires RhoB, a member of the Rho family of actin cytoskeletal regu...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The National Academy of Sciences
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC33444/ https://ncbi.nlm.nih.gov/pubmed/11353846 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.111137198 |
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