Cell Growth Inhibition by Farnesyltransferase Inhibitors Is Mediated by Gain of Geranylgeranylated RhoB

Recent results have shown that the ability of farnesyltransferase inhibitors (FTIs) to inhibit malignant cell transformation and Ras prenylation can be separated. We proposed previously that farnesylated Rho proteins are important targets for alternation by FTIs, based on studies of RhoB (the FTI-Rh...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Du, Wei, Lebowitz, Peter F., Prendergast, George C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 1999
Assuntos:	Cell Growth and Development
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10022870/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.3.1831
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