p21(Waf1/Cip1) Inhibition of Cyclin E/Cdk2 Activity Prevents Endoreduplication after Mitotic Spindle Disruption

During a normal cell cycle, entry into S phase is dependent on completion of mitosis and subsequent activation of cyclin-dependent kinases (Cdks) in G(1). These events are monitored by checkpoint pathways. Recent studies and data presented herein show that after treatment with microtubule inhibitors...

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Vydáno v:	Mol Cell Biol
Hlavní autoři:	Stewart, Zoe A., Leach, Steven D., Pietenpol, Jennifer A.
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Taylor & Francis 1999
Témata:	Cell Growth and Development
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC83879/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9858545/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.19.1.205
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